One in every 691 babies in the U.S. is born with Down syndrome, making it the most common genetic condition diagnosed in America. Of the three different types of Down syndrome, 400,000 Americas have at least one, yet  very little is known about the direct causes.

The lack of research advancements of this genetic condition is what inspired Michelle Pfeiffer, one of Cary Magazine's 2013 Women of Western Wake, to establish Anna’s Angels — The Anna Michelle Merrills Foundation for Down Syndrome Research.

To raise awareness and funds for research, the 11th annual Anna’s Angels Gala will be held on March 22 at 6:30 p.m., at the Prestonwood Country Club in Cary.

Tickets are $115 per person and include a night of dinner, dancing, and live and silent auctions.

Ever since the day her daughter Anna was diagnosed with Down syndrome, Pfeiffer has been determined to increase funds for the research that will help improve the cognitive and communicative abilities of individuals affected.

“Anna’s Angels gives hope, and encourages families to see what their children can accomplish,” said Pfeiffer.

Each year, the foundation honors someone who has overcome the obstacles of Down syndrome, and this year’s special guest is Sujeet Desai, a 31-year-old musician from New York City, who has perfected playing seven different musical instruments.

Desai has performed all over the world, and received many national and international awards for his talents, and advocacy for awareness.

As for the impact of Anna's Angels over the past decade, in addition to the $1 million that has already been raised, Pfeiffer’s goal is to raise $100,000 at this year’s gala.

The foundation is also holding an online auction the week before the gala, for supporters around the country who are unable to attend. All proceeds donated help support Down syndrome research at Duke Children’s Hospital.

Tickets for the event can be purchased online at annas-angels.org.